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DNLI · NASDAQ

Denali Therapeutics (DNLI) Stock Price & Fundamentals

$412.19−0.59%−$2.44End-of-day price as of Oct 9, 2026

Denali Therapeutics (DNLI) closed at $412.19 on Oct 9, 2026, down 0.59% from the previous close of $414.63.

Share price, past year

1Y +21.19%

52-week range $336.13 – $419.89. Daily closing prices.
Monthly closing prices
Last closing price of each month
DateClose
Oct 9, 2026$412.19
Sep 30, 2026$417.89
Aug 31, 2026$399.30
Jul 31, 2026$376.99
Jun 30, 2026$375.70
May 29, 2026$391.11
Apr 30, 2026$393.94
Mar 31, 2026$396.31
Feb 27, 2026$392.94
Jan 30, 2026$385.15
Dec 31, 2025$356.81
Nov 28, 2025$355.93
Oct 31, 2025$349.74

Key statistics

Market cap
$65.85B
P/E (TTM)
—
EPS (TTM)
−$2.84
Revenue (TTM)
—
Net income (TTM)
−$511.45M
Shares outstanding
159.8M
Dividend yield
—
52-week range
$336.13 – $419.89

Denali Therapeutics's market cap is $65.85B, based on a share price of $412.19 and 159.8M shares outstanding as of Jun 30, 2026.

Financials

Denali Therapeutics reported revenue of $0.00 for fiscal 2025.

Denali Therapeutics reported a net loss of $512.54M in fiscal 2025.

Annual revenue

FY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
Annual revenue by fiscal year; the table below lists the values.
Denali Therapeutics annual financials by fiscal year, from SEC filings
Fiscal yearRevenueGrowthNet incomeNet marginEPS (diluted)Free cash flow
FY2025ended Dec 31, 2025$0.00—−$512.54M—−$2.97−$422.10M
FY2024ended Dec 31, 2024$0.00−100.0%−$422.77M—−$2.57−$363.61M
FY2023ended Dec 31, 2023$330.53M+204.7%−$145.22M−43.9%−$1.06−$370.93M
FY2022ended Dec 31, 2022$108.46M+122.9%−$325.99M−300.6%−$2.60−$262.55M
FY2021ended Dec 31, 2021$48.66M−85.5%−$290.58M−597.2%−$2.39−$219.89M
FY2020ended Dec 31, 2020$335.66M+1,158.2%$71.14M21.2%$0.63$413.06M
FY2019ended Dec 31, 2019$26.68M−79.3%−$197.61M−740.7%−$2.07−$169.50M
FY2018ended Dec 31, 2018$129.16M—−$36.24M−28.1%−$0.39$46.72M
FY2017ended Dec 31, 2017$0.00—−$88.19M—−$5.89−$79.51M
FY2016ended Dec 31, 2016$0.00—−$86.65M—−$13.49−$78.04M
Denali Therapeutics quarterly results
QuarterRevenueNet incomeEPS (diluted)
Q2 FY2026ended Jun 30, 2026$3.60M−$127.55M−$0.68
Q2 FY2025ended Jun 30, 2025$0.00−$124.12M−$0.72
Q4 FY2024ended Dec 31, 2024$0.00−$114.75M−$0.67
Q3 FY2024ended Sep 30, 2024$0.00−$107.19M−$0.63
Q2 FY2024ended Jun 30, 2024$0.00——
Q1 FY2024ended Mar 31, 2024$0.00——
Q4 FY2023ended Dec 31, 2023$0.00——
Q3 FY2023ended Sep 30, 2023$1.27M——

Company profile

Name
Denali Therapeutics Inc.
Ticker
DNLI
Exchange
NASDAQ
Industry (SEC SIC)
Biological Products, (No Diagnostic Substances)
Headquarters
161 Oyster Point Blvd., South San Francisco, CA 94080
Incorporated in
DE
Fiscal year ends
December
SEC CIK
0001714899

Recent SEC filings

Frequently asked questions

What is Denali Therapeutics's stock price?

Denali Therapeutics (DNLI) closed at $412.19 on Oct 9, 2026, down 0.59% from the previous close of $414.63.

What is Denali Therapeutics's market cap?

Denali Therapeutics's market cap is $65.85B, based on a share price of $412.19 and 159.8M shares outstanding as of Jun 30, 2026.

How much revenue does Denali Therapeutics make?

Denali Therapeutics reported revenue of $0.00 for fiscal 2025.

Does Denali Therapeutics pay a dividend?

Denali Therapeutics's recent filings report no dividends declared over the last four quarters.

Sources and methodology

Fundamentals come from Denali Therapeutics Inc.'s filings with the SEC (EDGAR XBRL company facts). Fourth-quarter figures that companies don't report separately are calculated as the fiscal year minus the first three quarters. Trailing twelve-month (TTM) figures sum the latest four quarters. Prices are generated sample data for development. Last updated Oct 9, 2026. Data sources and disclosures